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Physician Profiles
Jacob Vadakekalam, M.D. |
EDUCATION
Fellowship - University of Wisconsin July 1993 – November 1996
Residency - Mayo Graduate School of Medicine, Rochester, MN June 1991 – June 1993
Medical School - St. John’s Medical College August 1975 – March 1981
Distinction in Microbiology, Bangalore University 1978
Certification in Densitometry
American Board of Endocrinology
American Board of Internal Medicine
M.R.C.P. London, U.K.
M.B.B.S. Bangalore, India
SCIENTIFIC SOCIETY MEMBERSHIPS
Texas Medical Association
Bexar County Medical Society
Washington State Medical Society
American Medical Association
American Diabetes Association
American College of Clinical Endocrinology
European Association for the Study of Diabetes
STAFF PHYSICIAN
CHRISTUS Santa Rosa Health Systems
2827 Babcock Road
San Antonio, Texas 78229
Southwest Texas Methodist Health Systems
7700 Floyd Curl Drive
San Antonio, Texas 78229
Methodist Specialty & Transplant Hospital
(Formerly San Antonio Community Hospital)
8026 Floyd Curl Drive
San Antonio, Texas 78229
Baptist Health Systems
7930 Floyd Curl Drive
San Antonio, Texas 78229
PUBLICATIONS
“A Defect Late in Stimulus-secretion Coupling Impairs Insulin Secretion in Goto-Kakizaki Diabetic Rats”. Metz, M.; Meredith, J.; Vadakekalam, J.; Rabaglia, M. Diabetes, 1999: 28; pp. 1754-62
“Isotopic Efflux Studies as Indices of Phopholipase Activation”. J. Vadakekalam and S. Metz. Methods in Molecular Biology, 1998: 105; pp. 175-185
“Interleukin-1 Inhibits Phospholipase-C and Insulin Secretion at Sites Apart From K+ (ATP) Channel”. J. Vadakekalam; M. Rabaglia and S. Metz. American Journal Physiology, 1997: 273; pp. E942-E950
“GTP-Dependent Stimulation of The Membrane Association and Carboxyl Methylation of CDC42 in Rodent and Human Pancreatic Islets and Pure Beta Cell: Evidence For an Essential Role in Nutrient-Induced Insulin Secretion”. A. Kowluri; S. Seavey; R. Sorenson; A.J. Weinhaus; R. Nesher; G. Li; M. Rabaglia; J. Vadakekalam and S. Metz. Journal of Clinical Investigation, 1996: 98; pp. 540-555
“Glucose-Induced Phosphoinositide Hydrolysis: A Requirement for GTP in Calcium-Induced Phospholipase-C Activation in Pancreatic Islets.” J. Vadakekalam; M. E. Rabaglia; Q-H Shen and S. Metz. American Journal of Physiology, 1996: 271; pp. E85-E95
“Glucose-Induced Phospholipase-C Activation is Dependent on GTP in Pancreatic Islets.” J. Vadakekalam; M. Rabaglia and S. Metz. Diabetologia, 1995:38 (supplement 1); p. 117A
“A Requirement for GTP in Glucose and Calcium-induced Phospholipase-C Activation in Pancreatic Islets.” J. Vadakekalam; M. Rabaglia and S. Metz. Diabetes, 1995: 44 (supplement 1); p. 189A
“A Requirement for GTP in Glucose-Induced Phosphoinositide Hydrolysis”. J. Vadakekalam; M. Rabaglia and S. Metz. Journal of Investigative Medicine. 1995:43; p. 170A
“Clinical Management of the NIDDM Patient: Impact of the American Diabetes Association Practice Guidelines, 1985-1993.” M. Stolar; The Endocrine Fellows Foundation Study Group. Diabetes Care, 1995:18; P. 701.
“GTP-Binding Proteins in the Cell: Regulation and Effects on Insulin Secretion. Proceedings of 15th International Diabetes Federation, Kobe, Japan 1995.” S. Metz; M. Meredith; J. Vadakekalam and A. Kowluru. Diabetes 1994, Elsevier Science B.V. pp. 228-234
Clinical Case Seminar; “Sometimes the Hooves do Belong to Zebras! An Unusual Case of Hypopituitarism.” J. Vadakekalam; T. Stamos and Y. Shenkar. Journal of Clinical Endocrinology & Metabolism, 1995: 80; P. 17
“Apoptosis – An Alternative Mechanism of Bile Salt Hepatotoxicity. In. Paumgartner G, Beuers U, eds. Bile Acids in Liver Diseases. T. Patel; J. Spivey; J. Vadakekalam and G. J. Gores. Kluwer Academic Publishers, Lancaster, England. Chapter 9:88
“Ursodeoxycholate Cytoprotection Against Hepatocyte Killing by Hydrophobic Bile Salts Cannot be Explained Solely by Changes in the Hydrophobic Index.” J. R. Spivey; J. Vadakekalam and G. J. Gores. HepatologyHepatology 1992 16:134A
“Complications of Laparoscopic Cholecystectomy: Perspective From a Referral Unit.” J. Vadakekalam and A. J. Czaja. Gastrointestinal Endoscopy 1992, 38:282
“Mycobacterium Fortuitum Lung Abscess Treated with Ciprofloxacin.” J. Vadakekalam and M. J. Ward. Thorax 1991, 46:737
“Thyroid Carcinomas in Kerala.” J. Vadakekalam. M.D. Thesis accepted by University of Kerala, 1986.
“COMMUNITY SCREENING FOR DIABETES: SHOULD DEMOGRAPHICS BE A FACTOR?” Mark S. Kipnes; Sherwyn L. Schwartz; Jerome S. Fischer; William F. Trigoso; Amna A. Salhin; Jacob Vadakekalam; Daina Dreimane and William D. Linn. Abstract submitted to the American Association of Clinical Endocrinologists 10th Annual Meeting & Clinical Congress. May 2-6, 2001. San Antonio, Texas.
“Stimulation by Glucose of Carboxyl Methylation of Specific GTP-Binding Proteins in Pancreatic Beta Cells”. A. Kowluri; S. Seavey; G. Li; J. Vadakekalam and S. Metz. Abstract submitted to the 10th International Congress of Endocrinology, June 12-15, 1996, San Francisco, CA. International Congress of Endocrinology, 1996: Vol 11; p 745.
“Role For GTP and Phospholipase-C in Potentiation of Calcium-Induced Insulin Secretion by Glucose in Rat Pancreatic Islets.” J. Vadakekalam, M. E. Rabaglia and S. Metz. Abstract submitted to the American Diabetes Association meeting June 8-11, 1996, San Francisco, CA.
“Pattern of Thyroid Cancers in Kerala.” J. Vadakekalam and Mr. Roy. Abstract submitted for annual meeting of Association of Physicians, held in Allahabad, India, January 1986.
“Impact of Use of Insulin, Glargine, on Hbg A1c and BMI in a Specialty (Endocrine) Practice Population.” Jerome S. Fischer, M.D. Riad G. Dirani, M.D., Sherwyn L. Schwartz, M.D., Mark S. Kipnes, M.D., Fernando
W. Trigoso, M.D., Amna A. Salhin, M.D., Jacob Vadakekalam, M.D., Daina Dreimane, M.D., Litza Loza, San Antonio, Texas. For presentation at the American Diabetes Association 62nd Scientific Sessions, June 14-18, 2002, San Francisco, California.
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